Protein-based drug design is a strategic approach used in the development of new drugs that target specific proteins involved in disease processes. It involves designing molecules, such as small molecules or biologics that interact with proteins to modulate their activity and achieve therapeutic effects. Protein-based drug design allows for the development of targeted therapies that specifically interact with disease-relevant proteins, offering the potential for greater efficacy and reduced side effects compared to non-specific treatments. However, it requires detailed knowledge of the target protein and its structure, as well as extensive experimental validation. This approach can be combined with other drug design strategies, such as ligand-based or structure-based approaches, to maximize the chances of success in identifying novel therapeutics.
