3D Bio printing may be a kind of cumulative manufacturing that uses cells and other biocompatible materials as “inks”, also appertained to as bio inks, to print living structures layer- by- layer which mimic the behaviour of natural living systems. Bio printed structures, like an organ- on-a-chip, are frequently used to study functions of a person's body outside the body (In-Vitro), in 3D. The figure of a 3D bio printed structure is more nearly like that of a present natural system than an in vitro study performed in 2D, and may be more biologically applicable. It’s used most naturally within the fields of tissue engineering and bioengineering, and accoutrements wisdom. 3D bio printing is also increasingly used for pharmaceutical development and medicine confirmation, and within the future are going to be used for medical operations in clinical settings – 3D printed skin grafts, bone grafts, implants, biomedical bias, and indeed full 3d printed organs are all active motifs of bio printing exploration.